RT @AlexOlmedoMD: The majority of treatments being proved for COVID-19 are off-label or compassionate used, so their efficacy and safety ca…
@eforero54 @AdalbertoLlinas @carlostororeuma @EstebanOrtizMD @LuisZuritaG @MerayoDr @DinaArr @hugh2922 @HospUninorte @PanlarJ Sin duda un punto muy interesante para la discusión https://t.co/PQfLNfBrBT cc @jaimesda
@PinGuaymas @lmamezcuag @Antilop41599213 @doctormacias No, no es cierto, 100 veces mejor que muera por la enfermedad que por medicamentos que tú administraste, adjunto evidencia https://t.co/yPxHbJxAeH. Se que nos duele en el orgullo no actuar agresivamen
Treating COVID-19—Off-Label and Compassionate Use and Clinical Trials During Pandemics https://t.co/BbyDXVY9ds
@VeritoI2020 @GaryFisher1212 @doctormosqueda Jajaja no te comparto un articulo del.jama que habla precisamente de lo que hablas https://t.co/yPxHbJfZn9
@NINFloyd @doctormosqueda No hay evidencia sólida de que funcione, administrar un fármaco sin estudios aleatorizados contra placebo es un crimen, una lectura que habla sobre eso https://t.co/yPxHbJfZn9
@JessarmandoGme1 @doctormosqueda Mejor que mueran por covid y no por acción del fármaco que administraste, que incluso con todo el amor del mundo, es tu culpa https://t.co/yPxHbJfZn9
@aguilarvelazqu2 @doctormosqueda https://t.co/yPxHbJfZn9. La respuesta
@EricDragoYT @ppmx94 @LeonmyInfo @doctormacias https://t.co/yPxHbJfZn9 el articulo completo
@ppmx94 @EricDragoYT @LeonmyInfo @doctormacias https://t.co/yPxHbJfZn9. El artículo completo para que lo lea
@LeonmyInfo @EricDragoYT @ppmx94 @doctormacias https://t.co/yPxHbJfZn9. El artículo completo para que lo lea
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
RT @BiotechMania: やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs…
やや古いがJAMAがCOVID-19パンデミックでRCT(ランダム化比較試験)の最重要性を指摘している。 ”The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments for COVID-19 and any other future outbreak.” https://t.co/BkXFpbrXhC https://t.co
RT @phellinckx: @zenutopia1 @MathieuMolimard https://t.co/1BQwV8bV4l "A common interpretation of off-label use and compassionate use of dr…
RT @phellinckx: @zenutopia1 @MathieuMolimard https://t.co/1BQwV8bV4l "A common interpretation of off-label use and compassionate use of dr…
@zenutopia1 @MathieuMolimard https://t.co/1BQwV8bV4l "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from the disease, but if the patient survived, they survived because of the given
@amelie_for_you https://t.co/1BQwV8bV4l "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from the disease, but if the patient survived, they survived because of the given drug. This is
💉 Entonces, hacer "uso compasivo" con la mayoría de estos fármacos es ilógico, pues estás apostando 7 contra 93, y lo más probable es que solo le hagas daño al paciente (favorezcas su muerte).🥺 Más info sobre uso compasivo en COVID, en este artículo: http
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
@RslewisSally @venkmurthy @barttels2 @bogdienache @pash22 @TheLancet @NEJM @AHRPorg @load_dependent https://t.co/NOBl0QSO22 "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from the dis
RT @phellinckx: @vineettiruvadi @load_dependent @BoussageonR @NaudetFlorian https://t.co/NOBl0QSO22 "A common interpretation of off-label u…
RT @phellinckx: @vineettiruvadi @load_dependent @BoussageonR @NaudetFlorian https://t.co/NOBl0QSO22 "A common interpretation of off-label u…
@vineettiruvadi @load_dependent @BoussageonR @NaudetFlorian https://t.co/NOBl0QSO22 "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from the disease, but if the patient survived, they
"Columna de opinión" del JAMA sobre el uso compasivo de medicamentos y ensayos clínicos ramdomizados durante pandemias. "Si el paciente murió, murió de la enfermedad, pero si el paciente sobrevivió, sobrevivió debido al medicamento administrado" https
RT @AndersPerner: Randomized care better than random care for both patients and societies Treating COVID-19—Off-Label and Compassionate Us…
RT @JAMA_current: Andrew Kalil essay on research doing the pandemic at https://t.co/KzdEZufp3J #JAMALive'
RT @JAMA_current: Andrew Kalil essay on research doing the pandemic at https://t.co/KzdEZufp3J #JAMALive'
RT @JAMA_current: Andrew Kalil essay on research doing the pandemic at https://t.co/KzdEZufp3J #JAMALive'
RT @JAMA_current: Andrew Kalil essay on research doing the pandemic at https://t.co/KzdEZufp3J #JAMALive'
Andrew Kalil essay on research doing the pandemic at https://t.co/KzdEZufp3J #JAMALive'
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @RevistaMFSamfyc: Tratamiento de COVID-19—uso de fármacos fuera de ficha técnica, uso compasivo y ensayos clínicos aleatorizados durante…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
Treating COVID-19—Off-Label and Compassionate Use and Clinical Trials During Pandemics https://t.co/bGIEOdpFEJ
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
RT @sl_rygard: "A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from…
"A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from the disease, but if the patient survived, they survived because of the given drug. This is not true.": https://t.co/lTBlQnrRPZ . #c
Tratamiento de COVID-19—uso de fármacos fuera de ficha técnica, uso compasivo y ensayos clínicos aleatorizados durante la pandemia https://t.co/9HqCAe2wg9 PMID 32208486
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @jdchiche: I thought we had learned that lesson but the past few weeks have shown it needs to be stated again...By the way, medical jour…
Mmmhhh.... https://t.co/agrlq5CYqT from @JAMA_current #covid19
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
“A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from the disease, but if the patient survived, they survived because of the given drug.”
RT @DrSamRay: Ok, maybe underplays the current trial efforts outside the US but still resonates. More so in children where the default resp…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
I thought we had learned that lesson but the past few weeks have shown it needs to be stated again...By the way, medical journals also have a role in this...
RT @DrSamRay: Ok, maybe underplays the current trial efforts outside the US but still resonates. More so in children where the default resp…
Exactly my point! https://t.co/GSGMZWoBgJ
Journal of Anesthesiology and Pain Research# Submit manuscript# article#reviews#covid-19#online at#https://www.scholarscentral.org/submission/anesthesiology-pain-research.html
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
Treating COVID-19—Off-Label and Compassionate Use and Clinical Trials During Pandemics https://t.co/mL7TKDp28U
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @DrSamRay: Ok, maybe underplays the current trial efforts outside the US but still resonates. More so in children where the default resp…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
"If the disease is not 100% lethal and it is not known whether the experimental drug would help or harm a patient (ie, a situation with true equipoise), then it is ethical to conduct an RCT." YES!! I would submit that NOT to perform RCTs would be the unet
RT @RitaRubin: An issue I recently raised in a story about convalescent plasma, which most US patients have received through an expanded ac…
RT @AndersPerner: Should be evident... Medicine is far from perfect, the problems are well known and so are the solutions. That is if we pr…
Ok, maybe underplays the current trial efforts outside the US but still resonates. More so in children where the default response is to say the numbers are too small. So roll out the remdesivir, anakinra, tociluzimab and high doses of steroids @PICJournalW
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @AndersPerner: Should be evident... Medicine is far from perfect, the problems are well known and so are the solutions. That is if we pr…
RT @JAMA_current: When a drug with unknown clinical effects is given to patients who have severe illness from a new disease like COVID-19,…
RT @AndersPerner: Should be evident... Medicine is far from perfect, the problems are well known and so are the solutions. That is if we pr…
Should be evident... Medicine is far from perfect, the problems are well known and so are the solutions. That is if we prioritize patients safety above other motives
An issue I recently raised in a story about convalescent plasma, which most US patients have received through an expanded access (compassionate use) protocol, not in randomized controlled trials https://t.co/PQIJJsMEJq
"A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from the disease, but if the patient survived, they survived because of the given drug. This is not true."
Excellent editorial on the importance of RCTs for COVID-19 therapies (also applies to mechanical ventilation strategies)