RT @ASPphysician: Treating #COVID19—Off-Label and Compassionate Use and Clinical Trials During Pandemics. A fantastic summary of the issue…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @SIDPharm: Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @BarnerIDpharmD: In the 2014 Ebola outbreak, numerous therapies were tested including chloroquine, hydroxychloroquine, favipiravir, brin…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @SIDPharm: Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and…
RT @BarnerIDpharmD: In the 2014 Ebola outbreak, numerous therapies were tested including chloroquine, hydroxychloroquine, favipiravir, brin…
In the 2014 Ebola outbreak, numerous therapies were tested including chloroquine, hydroxychloroquine, favipiravir, brincidofovir, and monoclonal antibodies. Ultimately, none proved to be efficacious or safe. #covidrx #TwitteRx #IDTwitter
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @bchouster: Science, science, science !
Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics" https://t.co/o8LJqgdKkh #COVIDRX #COVID19 #IDTwitter
RT @bchouster: Science, science, science !
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
…and that affected patients frequently have cardiac arrhythmias, chloroquine/hydroxychloroquine, azithromycin, and lopinavir-ritonavir could potentially increase the risk of cardiac death.” https://t.co/d0apGEwd4p
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
"The rapid and simultaneous combination of supportive care and RCTs (randomized controlled trials) is the only way to find effective and safe treatments for COVID-19 and any other future outbreak." https://t.co/w1fhE3EcQ5
Journal of the AMA says: "..no clinical evidence currently supports the efficacy and safety of any drug against any coronavirus in humans". https://t.co/mfNaUvABXn
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics | JAMA | JAMA Network https://t.co/wKTibuvUoM
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
“The administration of any unproven drug as a “last resort” wrongly assumes that benefit will be more likely than harm. A common interpretation of off-label use and compassionate use of drugs is that if the patient died, they died from the disease, but if
Andre Kalil, an infectious disease doctor at UNMC, makes a powerful and important case for randomized controlled trials during an epidemic. Chloroquine, HCQ and favipirarvir were all tried against the Ebola virus in 2014, too, he writes in JAMA: https:/
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
Science, science, science !
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
Compassionate use isn’t compassionate if we give our patients therapies that cause them more harm than good. The only way to prove the efficacy of new & off-label medicines is through RCTs. Our chinese colleagues have shown it’s possible, and we must f
New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do research. Emergency situations not an excuse for shortcuts Everyone reads this @JAMA_current https://t.co/xszTbJkvYq
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
So true!
Tratamiento de COVID-19: uso no autorizado de medicamentos, uso compasivo y ensayos clínicos aleatorizados durante pandemias | JAMA | Red JAMA https://t.co/Kv9Auk8JN5
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
during an outbreak, the type of RCTs that should be prioritized are ones with an adaptive design, which are able to rapidly accept or reject multiple experimental therapies throughout the trial, while being adequately powered for meaningful clinical outcom
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments for #COVID19 and any other future outbreak https://t.co/INavfNXwUv