RT @HeartOTXHeartMD: Treating #COVID19—Off-Label Drug Use, Compassionate Use, and #RandomizedClinicalTrials During #Pandemics https://t.co…
Treating #COVID19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During #Pandemics | @JAMA | @JAMANetwork Andre C. Kalil, MD @unebraska https://t.co/nLEZ4NmJBT
RT @pash22: Treating COVID-19 #coronavirus —Off-Label Drug Use, Compassionate Use & RCTs During Pandemics: it is critical 2 evaluate these…
RT @SteveJoffe: This in @JAMA_current, 1000 times. We need controlled trials, not uncontrolled use, to figure out what works against COVID.…
RT @SIDPharm: Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
"A common interpretation of off-label use and compassionate use of drugs is that is that if the patient died, they died from the disease, but if the patient survived, they survived because of the given drug. This is not true." https://t.co/jgSwEJX0vt
Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics | A very important VP in @JAMA_current https://t.co/ZRSfYyPRdN
RT @pash22: Treating COVID-19 #coronavirus —Off-Label Drug Use, Compassionate Use & RCTs During Pandemics: it is critical 2 evaluate these…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @luisamnMD: “The administration of any unproven drug as a “last resort” wrongly assumes that benefit will be more likely than harm. A co…
RT @SteveJoffe: This in @JAMA_current, 1000 times. We need controlled trials, not uncontrolled use, to figure out what works against COVID.…
RT @RichardJHankins: Great viewpoint in JAMA by Dr Andre Kalil on the need of RCTs in a pandemic. Agree that in off label use patient death…
Treating #COVID19—Off-Label Drug Use, Compassionate Use, and #RandomizedClinicalTrials During #Pandemics https://t.co/1tKQcmd6cR
Treating COVID-19 #coronavirus —Off-Label Drug Use, Compassionate Use & RCTs During Pandemics: it is critical 2 evaluate these drugs in studies that have a concurrent control group https://t.co/DGt4ON31Dn via @JAMA_current & @unmc 's #AndreKalil @A
"It is imperative to discover new therapies, otherwise there will be no proven treatments for future coronavirus pandemics." Treating COVID-19—Off-Label and Compassionate Use and Clinical Trials During Pandemics https://t.co/QZfaIbZDxT @catcotrial
Compassionate use -- while well intended -- may do more harm than good. The importance of RCTs to assess novel coronavirus treatment https://t.co/ez17UjCVQq
RT @PeterKilmarx: "The rapid and simultaneous combination of supportive care and #RandomizedControlledTrials is the only way to find effect…
RT @SteveJoffe: This in @JAMA_current, 1000 times. We need controlled trials, not uncontrolled use, to figure out what works against COVID.…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @SteveJoffe: This in @JAMA_current, 1000 times. We need controlled trials, not uncontrolled use, to figure out what works against COVID.…
Treating COVID-19—Off-Label and Compassionate Use and Clinical Trials During Pandemics https://t.co/k2amAJ9mki
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @SteveJoffe: This in @JAMA_current, 1000 times. We need controlled trials, not uncontrolled use, to figure out what works against COVID.…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics | JAMA | JAMA Network. technical document but provides an overview of the need for new COVID therapies to undergo randomized trials, historical view
Treating COVID-19—Off-Label and Compassionate Use and Clinical Trials During Pandemics https://t.co/pIyx71rPs2
"The rapid and simultaneous combination of supportive care and #RandomizedControlledTrials is the only way to find effective and safe treatments for #COVID19 and any other future outbreak." #FactsNotFear https://t.co/A1ZeDnL8nP
Everyone be thoughtful out there
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @RichardJHankins: Great viewpoint in JAMA by Dr Andre Kalil on the need of RCTs in a pandemic. Agree that in off label use patient death…
“When a drug with unknown clinical effects is given to patients who have severe illness from a new disease (like COVID-19), there is no way to know whether the patients had benefited or were harmed if they were not compared to a concurrent control group.”
El deseo de todo médico es ser activo en el manejo, a veces hay que esperar y hacer lo que se sabe, por que por querer hacer mas podemos hacer daño #zenintensivist https://t.co/5tMmkS7iah
RT @crisdelgor75: Tratamiento de COVID-19: uso no autorizado de medicamentos, uso compasivo y ensayos clínicos aleatorizados durante pandem…
RT @ferortegamd: dejare esto x aquí ! Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandem…
RT @SIDPharm: Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and…
@MPalaciosmd Este articulo me parece preciso para el momento. Mira maestro https://t.co/cgGhVAuFWA
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @MuinJKhoury: “It is imperative to discover new therapies. Otherwise, there will be no proven treatments for future coronavirus pandemic…
RT @NedPagliarulo: Andre Kalil, an infectious disease doctor at UNMC, makes a powerful and important case for randomized controlled trials…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
Il est essentiel de garder la raison et de travailler à faire progresser la connaissance. Gardons nous de faire des conclusions hâtives. #Covid_19fr #MIR #RestezChezVous #Raoult https://t.co/co4WeuScYL
@RHH_ICU @DudleyGroupNHS @themeddirector Excellent detailed article explaining the rationale for the need for trials & why not to rush into giving unproven, harmful drugs.
RT @SIDPharm: Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @RichardJHankins: Great viewpoint in JAMA by Dr Andre Kalil on the need of RCTs in a pandemic. Agree that in off label use patient death…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
.@JAMA_current JAMA/A Kalil: Treating #COVID19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics https://t.co/ICzWsAuZb1
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
Let us stick to science and EB controlled trials before assuming this or that molecule is efficacious # it is our responsibility as we do every day in the management of this pandemic
RT @RichardJHankins: Great viewpoint in JAMA by Dr Andre Kalil on the need of RCTs in a pandemic. Agree that in off label use patient death…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
Excellent article by Dr. Andre Khalil @unmc —- Treating COVID-19—Off-Label and Compassionate Use and Clinical Trials During Pandemics https://t.co/uMXe41iLPA
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @NedPagliarulo: Andre Kalil, an infectious disease doctor at UNMC, makes a powerful and important case for randomized controlled trials…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @JAMA_current: The rapid and simultaneous combination of supportive care and RCTs is the only way to find effective and safe treatments…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
Words in this week’s @JAMA_current from @UNMC @UNMC_ID’s own Andre Kalil, PI of the @NIH #RCT on #remdesivir for the treatment of #COVID19. Good science is always better than good anecdote, even in times like these!
Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics | JAMA | JAMA Network. Aux personnes qui en France se sont converties en médecins en qques jours et qui savent tout mieux que quiconque https://t.co/l5
RT @SIDPharm: Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and…
Excellent, timely article. "The administration of any unproven drug as a 'last resort' wrongly assumes that benefit will be more likely than harm."
RT @BarnerIDpharmD: In the 2014 Ebola outbreak, numerous therapies were tested including chloroquine, hydroxychloroquine, favipiravir, brin…
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @SIDPharm: Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and…
dejare esto x aquí ! Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics | JAMA | JAMA Network https://t.co/WoifSZk44g
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @SIDPharm: Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and…
Another good article. Although it is somewhat sad that few seem to get this message. Treating COVID-19—Off-Label and Compassionate Use and Clinical Trials During Pandemics https://t.co/Pfhv3uff31
RT @RichardJHankins: Great viewpoint in JAMA by Dr Andre Kalil on the need of RCTs in a pandemic. Agree that in off label use patient death…
RT @SIDPharm: Check out the latest viewpoint published today in @JAMA_current "Treating COVID-19—Off-Label Drug Use, Compassionate Use, and…
Pandemilerdeki çalışmalara dikkat, endikasyon dışı ilaç kullanımına dikkat, önce zarar verme #COVID19 #coronavirus Treating COVID-19—Off-Label and Compassionate Use and Clinical Trials During Pandemics https://t.co/YJ9ZhDHNDW
RT @RichardJHankins: Great viewpoint in JAMA by Dr Andre Kalil on the need of RCTs in a pandemic. Agree that in off label use patient death…
RT @RichardJHankins: Great viewpoint in JAMA by Dr Andre Kalil on the need of RCTs in a pandemic. Agree that in off label use patient death…
“It is imperative to discover new therapies. Otherwise, there will be no proven treatments for future coronavirus pandemics.” On the importance of RCTs during #covid19 pandemic. Via @JAMA_current https://t.co/sZjtChxdFa https://t.co/MvNZKyAzlZ
RT @DrMCecconi: New drugs during this pandemic? First do not harm. If seeking benefit, do not assume no harm. We have the tools to do resea…
RT @RichardJHankins: Great viewpoint in JAMA by Dr Andre Kalil on the need of RCTs in a pandemic. Agree that in off label use patient death…
Great viewpoint in JAMA by Dr Andre Kalil on the need of RCTs in a pandemic. Agree that in off label use patient deaths can too easily be blamed on disease, while patient survival must be the drug. @nvhstewart @KellyCawcuttMD @UNMC_ID @DrJRMarcelin https:/
RT @ASPphysician: Treating #COVID19—Off-Label and Compassionate Use and Clinical Trials During Pandemics. A fantastic summary of the issue…