@samarsheoran @froman1960 Bullshit, awful grift. The evidence does not support your claim >> https://t.co/y5kfh0HrbR
Population-based studies show people who have high LDL cholesterol levels, tend to have a high risk of heart disease. https://t.co/ejJ99Kboko
@CSmuclovisky @Heart_SCCT LDL (ApoB) causes ASCVD. I've posted this for you many times. You are ignoring data and science. https://t.co/8bEsxkN6F8
@purpleveganlady @TuckerGoodrich Check the COI of that study. Also note this: "Travel and meeting logistics were supported by unrestricted educational grants from MSD and Amgen to the European Atherosclerosis Society." https://t.co/BVZByt633u
@TuckerGoodrich @ToYourHealth101 COI is rather impressive on this one, too: https://t.co/BVZByt633u
@TuckerGoodrich This is the study that figure comes from just an FYI. It’s an extremely comprehensive look at LDL and ASCVD and worth a read. This figure from it comparing achieved LDL and CVD might be more striking. This contains both primary and seconda
RT @fsapradana: Penurunan kolesterol LDL dapat menurunkan risiko penyakit jantung koroner Perbanyak serat, kurangi lemak jenuh dan lemak t…
RT @fsapradana: Penurunan kolesterol LDL dapat menurunkan risiko penyakit jantung koroner Perbanyak serat, kurangi lemak jenuh dan lemak t…
RT @fsapradana: Penurunan kolesterol LDL dapat menurunkan risiko penyakit jantung koroner Perbanyak serat, kurangi lemak jenuh dan lemak t…
RT @fsapradana: Penurunan kolesterol LDL dapat menurunkan risiko penyakit jantung koroner Perbanyak serat, kurangi lemak jenuh dan lemak t…
RT @fsapradana: Penurunan kolesterol LDL dapat menurunkan risiko penyakit jantung koroner Perbanyak serat, kurangi lemak jenuh dan lemak t…
RT @fsapradana: Penurunan kolesterol LDL dapat menurunkan risiko penyakit jantung koroner Perbanyak serat, kurangi lemak jenuh dan lemak t…
@DoctorTro @realDaveFeldman @SBakerMD This is very similar to saying that there are many people who smoke that don’t get lung cancer. We have very good evidence that LDL plays a causal role in cardiovascular disease just as we have good evidence that smok
RT @realDaveFeldman: 3/ Also in the name of arguably the most cited meta-analysis for the Lipid Hypothesis to date: "Low-density Lipoprote…
3/ Also in the name of arguably the most cited meta-analysis for the Lipid Hypothesis to date: "Low-density Lipoproteins cause atherosclerotic cardiovascular disease" This meta combines lines from genetic, observational, and interventional studies. http
@holmanm It’s both. LDL plays a causal role in CVD and insulin resistance/inflammation are also very important risk factors! Statins actually decrease LDL and inflammation resulting in significantly decreased CVD. Read below, the evidence is overwhelming
@ktimesk Should be in the Brian Ference article https://t.co/Zld2dpSu6K
@Wickedlipid It's actually causative. https://t.co/8bEsxkN6F8
@jasinsight @JW72559513 @TheCarnivoreLaw Sure it isn't *causal* in the way LDL is clinically proven to cause atherosclerosis, but the *risk* of cancer increases with higher animal product consumption. Y'all never ask for sources though, you just get defens
@MasalaFry69 @realDaveFeldman Perhaps in your alternate dimension, there isn't any experimental evidence for causality, but there is in mine. See table 1, point 8. https://t.co/7oj1FDEKKD
@hmatejx @RWJE_BA @AdanZBecerra1 @camjpatrick @analisereal @beenwrekt @yudapearl But see for example how pluralism and pragmatism make surrogated endpoint useful sometimes: https://t.co/U1EuALVRXB
@drkohilathas I can't see how LDL-C independently means nothing, given this paper. The evidence is too strong. https://t.co/roA6O7f7M9 https://t.co/G9BiwNPFGf
@MasalaFry69 @exfatloss @richcollins @sguyenet Have you read and internalized this yet? https://t.co/7oj1FDEKKD
@ifbacongrewont1 @MohammedAlo "Hack science" -- a graphic showing effects of LDL-C lowering vs. CHD risk reduction in dozens of studies of three types: RCTs, prospective cohort, and Mendelian randomization. Here's the summary-of-evidence 2017 article conta
@drkohilathas I don't see it, if most sources of SFA increase levels of ApoB, and ApoB is causally related to atherosclerosis; using other, lesser powerful pieces of evidence doesn't make much sense to me. https://t.co/uIiMGuJfrq
@InquizitiveOne @SBakerMD https://t.co/dxhssBd2RB ok that's one study vs dozens of others. Why does the study you showed me hold more weight than this meta analysis? https://t.co/F7GK0EBGEc
We know LDL is a causative factor for atherosclerosis in the arteries. https://t.co/2t5QecYX7s Since high saturated fat intake increases LDL it is an indirect factor for cardiovascular disease.
@MasalaFry69 @ingold22 @SonicCruise @Drlipid I am impressed with your ability not to notice all the other evidence (it's not merely observational) that LDLs cause atherosclerosis. As I said above, you don't know what you criticize, and it makes you seem co
@LLicit_Tweet @DoctorTro He doesn't understand science. Greatest article ever written on LDL based on Chochrane database by Brian Ference. https://t.co/8bEsxkN6F8
https://t.co/YwfKvbyMsA "I am the healing herb."--Bhagavan Sri Krishna from Srimad Bhagavad-Gita, Bhishma Parva, Mahabharata
. . . there's a dose-dependent relationship between the amount of vascular exposure to LDL-C and the risk of cardiovascular disease. https://t.co/VABqTxBiet 2/2
@KetoCounselor If someone is really going to decide this for themselves and not use someone with expertise on the issue, they really should at a minimum read both sides, not just a hand-picked article. https://t.co/uyw31H8sLF
@MasalaFry69 @NutritionMadeS3 @PavlicaDanijel @robertlufkinmd @fproofmastery @theproof @Drlipid @FusionProgGuy @Paddy_Barrett Most comprehensive article on LDL https://t.co/8bEsxkN6F8
@LouS58384482 @ifixhearts Read this. https://t.co/8bEsxkN6F8
@DrReality5 @garytaubes What part of this do you consider pseudo science? https://t.co/rkqCL5Evvc
@stephensenn Are you aware of the ESC consensus statement on LDL? I would like to ask your opinion on this graph, thank you very much. https://t.co/IUMs4xBCSD https://t.co/W5NnPCGpSL
@of_skeptical @Dsout1234 @LaurenInTheWild There is evidence from interventional studies and mendelian randomization studies as well, and they show the same results. Here is a summary of all the different forms of evidence, observational and otherwise. http
@MaribethSchmidt @LauraBuchananMD If your LDL is high, then you want to get it down because higher LDL increases the risk of heart disease, all else equal. If on a low-carbohydrate diet, just focus on eating mostly unsaturated fats and getting plenty of fi
@darcys22 @PeterAttiaMD And also have a skim through the studies linked by @Drlipid here: https://t.co/qIpNQXTc2K
@venture_guru Haha you linked the pubmed article & then 2 articles talking about it. Here is a rebuttal to it > https://t.co/y5kfh0HrbR And > https://t.co/p1i0xlXCew & reversed chronic disease? What is the evidence for that? Was it done in
RT @DrNadolsky: @TraderMick_ Take a gander of these reviews https://t.co/Ug1jQdWdYP https://t.co/Iug7jxLUrn it's not one rct or one epi…
@TraderMick_ Take a gander of these reviews https://t.co/Ug1jQdWdYP https://t.co/Iug7jxLUrn it's not one rct or one epi study but a conglomerate of pathophys, rcts, genetics, and epi
@MacroView02 @FKetobear @dr_cois There isn't a shift. No paradigm shift. https://t.co/TVS09etM5J
#twitterheartspaces Key thing discussion is missing is the importance of time of LDL-C/apoB exposure. Early low LDL-C/apoB can have 3x the effect seen in drug trials. FOURIER was a short trial. https://t.co/vm96pSZ487 https://t.co/uZI761W5hn
@Bart_WT_Kay @theproof Wrong. "Consistent evidence from numerous and multiple different types of clinical and genetic studies unequivocally establishes that LDL causes ASCVD" https://t.co/Nuw4EvEhnp https://t.co/VlYLwxTahV
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
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RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
RT @EstebanDL: ¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https:…
¿Cuál es el peor artículo "científico" que leiste? Te dejo el mio: https://t.co/Sr7eebGxPN Y te lo Explico abajo👇👇👇 https://t.co/my76KebmGK
@SBakerMD European Atherosclerosis Society gives several lines of concordant evidence (based on genetic, epidemiologic, and clinical studies) on why LDC is indeed causal https://t.co/OgmULlRMPg
@SBakerMD If genetically you have high LDL, then you get significantly increased CVD death rate (familial hypercholesterolemia can increase risk up to 20x). Opposite is true if genetically you have low LDL. Hard to argue not important https://t.co/OgmULlR
@RationalStoic @RahmanianBob @DoctorTro European Atherosclerosis Society gives several reasons (based on genetic, epidemiologic, and clinical studies) why LDC is indeed causal https://t.co/OgmULlRMPg
@lenard_jakub @medmyths Not true. See below from @AustinBaraki https://t.co/8yuh3gbPTk
@medmyths I said "assuming other factors, e.g., blood pressure, didn't worsen" ➡️ torcetrapib ⬆️ blood pressure. https://t.co/fdV1DNt8K3 If you can show an instance where, all else held equal, lower LDL/apoB caused harm, I am interested. See 👇 from @Austi
@medmyths In RCTs, roughly 10-20% reduction in CHD risk (over a median 5-year period) per 0.50-1.00 mmol/L reduction. In prospective cohorts (median follow-up 12 years), risk reduction is approx. 18-50%. Small ⬇️ in abs. risk prevents thousands of events i
@ChrispLMarshall @sos_intern @jonnyob @Crzy_Diamond @holmanm https://t.co/EcJgztybqy No problem. This is the consensus statement from the EAS on LDL & Cardiovascular disease
@258_646 @MasalaFry69 @NutritionMadeS3 What about genetic studies https://t.co/roA6O7fFBH
Thanks! Not sure what your point is. I believe you graph is of cohort study (association) data. My #s come directly from the key large multiyear RCTs (cause and effect). Or am I missing something? Would also love to hear how you deal with LDL measurement v
@medmyths Risk is likely underestimated owing to the relatively short timeframe of RCTs. If we look at those with genetically lower LDL-C, we see ⬇️ CHD risk of approx. 15% for 0.20 mmol/L lower concentration, to a >50% ⬇️ in risk for 1.00 mmol/L lower
@bfhhealth @iwantthescience @NutritionMadeS3 @Bart_WT_Kay @theproof Another nothing burger from Kay with ZERO outcome based data from quality studies in humans. The coward keeps running away from engaging all experts. For actual science: https://t.co/rkqCL
@BrucePugh16 @theproof Well, we know high ApoB has causal inference in CVD since literally all types of studies point for over 90% in the exact same direction. https://t.co/rkqCL5mmh4
@Travis_Statham I am not a vegan, just someone who goes by actual outcome based data from quality studies in humans. You should try it. https://t.co/rkqCL5mmh4
@MathieuChiasson @theproof In 280 characters, eh 😉 ? I'm guessing you're not a subscriber to @peterattiamd, but if you do, starting here at 15:00 would be useful https://t.co/zFdyfzTsbU These are useful on their own or to supplement https://t.co/YruqDfyn2
@TheBrainBattery Results from a genetic study on LDL-C: A 1-standard deviation increase in genetically proxied LDL-c was associated with 1.2 years lower lifespan. https://t.co/MbJnUdqx71 And just in case your not convinced about LDL-C (or ApoB): https://t
RT @theproof: 4/ For more information on why high LDL-C is a bad idea I suggest reading the below paper by Cardiologist Brian Ference. In…
@sesilgoke @TahsinOnemli @agustos13 30 yıl önce ortaya atılmış ve hiçbir bilimselliği olmayan yalanla ilgili sahip olduğumuz kanıtlara bak. Tıp tarihinde belki hiçbir konu bu kadar araştırılmamıştır ve bu kadar iyi kanıtlara sahip değildir. Tablo 1 https:/