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Pharmacogenomics

Overview of attention for book
Cover of 'Pharmacogenomics'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Pharmacogenomics: Historical Perspective and Current Status
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    Chapter 2 Denaturing High-Performance Liquid Chromatography for Mutation Detection and Genotyping
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    Chapter 3 Clinical SNP Detection by the SmartAmp Method
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    Chapter 4 Maldi-tof mass spectrometry.
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    Chapter 5 TaqMan ® Drug Metabolism Genotyping Assays for the Detection of Human Polymorphisms Involved in Drug Metabolism
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    Chapter 6 Pyrosequencing of Clinically Relevant Polymorphisms
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    Chapter 7 Pharmacogenetics Using Luminex ® xMAP ® Technology: A Method for Developing a Custom Multiplex Single Nucleotide Polymorphism Mutation Assay
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    Chapter 8 Use of linkage analysis, genome-wide association studies, and next-generation sequencing in the identification of disease-causing mutations.
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    Chapter 9 The GoldenGate Genotyping Assay: Custom Design, Processing, and Data Analysis
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    Chapter 10 Genome-Wide Gene Expression Profiling, Genotyping, and Copy Number Analyses of Acute Myeloid Leukemia Using Affymetrix GeneChips
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    Chapter 11 Epigenetic Techniques in Pharmacogenetics
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    Chapter 12 Plasmid Derived External Quality Controls for Genetic Testing
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    Chapter 13 Allelic Imbalance Assays to Quantify Allele-Specific Gene Expression and Transcription Factor Binding
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    Chapter 14 SCAN: A Systems Biology Approach to Pharmacogenomic Discovery
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    Chapter 15 Methods to Examine the Impact of Nonsynonymous SNPs on Protein Degradation and Function of Human ABC Transporter
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    Chapter 16 In Vitro Identification of Cytochrome P450 Enzymes Responsible for Drug Metabolism
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    Chapter 17 In Vitro and In Vivo Mouse Models for Pharmacogenetic Studies
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    Chapter 18 The Hydrodynamic Tail Vein Assay as a Tool for the Study of Liver Promoters and Enhancers
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    Chapter 19 A guide to the current web-based resources in pharmacogenomics.
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    Chapter 20 PharmGKB: The Pharmacogenomics Knowledge Base
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    Chapter 21 Genetic Databases in Pharmacogenomics: The Frequency of Inherited Disorders Database (FINDbase).
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    Chapter 22 Development of Predictive Models for Estimating Warfarin Maintenance Dose Based on Genetic and Clinical Factors
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    Chapter 23 Evidence Based Drug Dosing and Pharmacotherapeutic Recommendations per Genotype
Attention for Chapter 4: Maldi-tof mass spectrometry.
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About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

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2 X users

Citations

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Readers on

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385 Mendeley
Chapter title
Maldi-tof mass spectrometry.
Chapter number 4
Book title
Pharmacogenomics
Published in
Methods in molecular biology, January 2013
DOI 10.1007/978-1-62703-435-7_4
Pubmed ID
Book ISBNs
978-1-62703-434-0, 978-1-62703-435-7
Authors

Dirk van den Boom, Matthias Wjst, Robin E. Everts, Boom, Dirk van den, Wjst, Matthias, Everts, Robin E.

Abstract

Major strengths of mass spectrometry analysis include the accuracy of the detection principle, automatic data storage as well as simplicity and flexibility of assay design making it a premier choice for targeted genotyping of sequence variations. We explain the assay principle in detail and give step-by-step laboratory instructions. Finally, references point toward further use of mass spectrometry analysis for molecular haplotyping, re-sequencing, and quantitative analysis for copy number variations and gene expression studies are given.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 385 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 3 <1%
United States 2 <1%
Portugal 1 <1%
India 1 <1%
Latvia 1 <1%
Argentina 1 <1%
Canada 1 <1%
Unknown 375 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 78 20%
Student > Ph. D. Student 69 18%
Student > Master 57 15%
Researcher 56 15%
Student > Postgraduate 11 3%
Other 32 8%
Unknown 82 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 83 22%
Biochemistry, Genetics and Molecular Biology 66 17%
Chemistry 61 16%
Medicine and Dentistry 22 6%
Pharmacology, Toxicology and Pharmaceutical Science 11 3%
Other 46 12%
Unknown 96 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2013.
All research outputs
#14,628,184
of 22,713,403 outputs
Outputs from Methods in molecular biology
#4,597
of 13,079 outputs
Outputs of similar age
#173,404
of 280,747 outputs
Outputs of similar age from Methods in molecular biology
#163
of 341 outputs
Altmetric has tracked 22,713,403 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,079 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,747 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 341 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.