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ALK-Testing in non-small cell lung cancer (NSCLC): Immunohistochemistry (IHC) and/or fluorescence in-situ Hybridisation (FISH)?

Overview of attention for article published in Lung Cancer (01695002), January 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (59th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

patent
1 patent

Citations

dimensions_citation
19 Dimensions

Readers on

mendeley
14 Mendeley
Title
ALK-Testing in non-small cell lung cancer (NSCLC): Immunohistochemistry (IHC) and/or fluorescence in-situ Hybridisation (FISH)?
Published in
Lung Cancer (01695002), January 2017
DOI 10.1016/j.lungcan.2016.11.008
Pubmed ID
Authors

M. von Laffert, P. Schirmacher, A. Warth, W. Weichert, R. Büttner, R.M. Huber, J. Wolf, F. Griesinger, M. Dietel, Ch. Grohé

Abstract

The EML4-ALK pathway plays an important role in a significant subset of non-small cell lung cancer patients. Treatment options such as ALK tyrosine kinase inhibitors lead to improved progression free survival and overall survival. These therapeutic options are chosen on the basis of the identification of the underlying genetic signature of the EML-ALK translocation. Efficient and easily accessible testing tools are required to identify eligible patients in a timely fashion. While FISH techniques are commonly used to detect this translocation, the broad implementation of this type of ALK testing into routine diagnostics is not optimal due to technical, structural and financial reasons. Immunohistochemical techniques to screen for EML4-ALK translocations may therefore play an important role in the near future. This consensus paper provides recommendations for the test algorithm and quality of the respective test approaches, which are discussed in the light of the current literature.

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 21%
Researcher 3 21%
Other 1 7%
Student > Bachelor 1 7%
Unknown 6 43%
Readers by discipline Count As %
Medicine and Dentistry 4 29%
Biochemistry, Genetics and Molecular Biology 2 14%
Psychology 1 7%
Agricultural and Biological Sciences 1 7%
Unknown 6 43%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 April 2020.
All research outputs
#5,635,451
of 17,429,432 outputs
Outputs from Lung Cancer (01695002)
#623
of 2,229 outputs
Outputs of similar age
#102,456
of 277,522 outputs
Outputs of similar age from Lung Cancer (01695002)
#15
of 37 outputs
Altmetric has tracked 17,429,432 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,229 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,522 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.