| Title |
Acute Poisonings from Synthetic Cannabinoids - 50 U.S. Toxicology Investigators Consortium Registry Sites, 2010-2015.
|
|---|---|
| Published in |
MMWR: Morbidity & Mortality Weekly Report, July 2016
|
| DOI | 10.15585/mmwr.mm6527a2 |
| Pubmed ID | |
| Authors |
Anne M Riederer, Sharan L Campleman, Robert G Carlson, Edward W Boyer, Alex F Manini, Paul M Wax, Jeffrey A Brent |
| Abstract |
Recent reports suggest that acute intoxications by synthetic cannabinoids are increasing in the United States (1,2). Synthetic cannabinoids, which were research compounds in the 1980s, are now produced overseas; the first shipment recognized to contain synthetic cannabinoids was seized at a U.S. border in 2008 (3). Fifteen synthetic cannabinoids are Schedule I controlled substances (3), but enforcement is hampered by the continual introduction of new chemical compounds (1,3). Studies of synthetic cannabinoids indicate higher cannabinoid receptor binding affinities, effects two to 100 times more potent than Δ(9)-tetrahydrocannabinol (the principal psychoactive constituent of cannabis), noncannabinoid receptor binding, and genotoxicity (4,5). Acute synthetic cannabinoid exposure reportedly causes a range of mild to severe neuropsychiatric, cardiovascular, renal, and other effects (4,6,7); chronic use might lead to psychosis (6,8). During 2010-2015, physicians in the Toxicology Investigators Consortium (ToxIC) treated 456 patients for synthetic cannabinoid intoxications; 277 of the 456 patients reported synthetic cannabinoids as the sole toxicologic agent. Among these 277 patients, the most common clinical signs of intoxication were neurologic (agitation, central nervous system depression/coma, and delirium/toxic psychosis). Relative to all cases logged by 50 different sites in the ToxIC Case Registry, there was a statistically significant association between reporting year and the annual proportion of synthetic cannabinoid cases. In 2015, reported cases of synthetic cannabinoid intoxication increased at several ToxIC sites, corroborating reported upward trends in the numbers of such cases (1,2) and underscoring the need for prevention. |
X Demographics
The data shown below were collected from the profiles of 63 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 31 | 49% |
| Mexico | 1 | 2% |
| United Kingdom | 1 | 2% |
| Venezuela, Bolivarian Republic of | 1 | 2% |
| Ireland | 1 | 2% |
| Brazil | 1 | 2% |
| Qatar | 1 | 2% |
| Unknown | 26 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 38 | 60% |
| Practitioners (doctors, other healthcare professionals) | 12 | 19% |
| Scientists | 10 | 16% |
| Science communicators (journalists, bloggers, editors) | 3 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 1% |
| Unknown | 89 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 16% |
| Student > Master | 11 | 12% |
| Other | 10 | 11% |
| Student > Ph. D. Student | 10 | 11% |
| Student > Bachelor | 9 | 10% |
| Other | 24 | 27% |
| Unknown | 12 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 33 | 37% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 13% |
| Psychology | 5 | 6% |
| Chemistry | 3 | 3% |
| Neuroscience | 3 | 3% |
| Other | 18 | 20% |
| Unknown | 16 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 625. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2022.
All research outputs
#35,917
of 25,562,515 outputs
Outputs from MMWR: Morbidity & Mortality Weekly Report
#522
of 4,258 outputs
Outputs of similar age
#693
of 372,732 outputs
Outputs of similar age from MMWR: Morbidity & Mortality Weekly Report
#9
of 96 outputs
Altmetric has tracked 25,562,515 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,258 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 336.3. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 372,732 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.