RT @suzuki_takaya: このSHERLOCKの一つの醍醐味はレポーターの蛍光カラーを変えたりすることで一つのウエルでマルチプレックスな解析ができることです。 https://t.co/kyBY6dyTHW
このSHERLOCKの一つの醍醐味はレポーターの蛍光カラーを変えたりすることで一つのウエルでマルチプレックスな解析ができることです。 https://t.co/kyBY6dyTHW
We used an early version of ADAPT for the CARMEN v1 paper: https://t.co/YqCV0xRrQ6, and in turn used CARMEN to power ADAPT with >19,000 crRNA-target pairs
6/ To learn a model we need a dataset. We screened ~20K CRISPR-Cas13 diagnostic guide-target pairs (made possible by CARMEN 👇). The pairs: • span viral diversity • emphasize target mutations Each pair’s fluorescent readout over time ≈ its sensitivity. htt
Massively multiplexed nucleic acid detection with Cas13 - Nature https://t.co/DdECXTmPMx
In just two years, Tinna developed CRISPR-based diagnostics for SARS-CoV-2, flu, & other viruses, working closely w/ @cambearon & @AriztiSanz. She contributed to papers in @Nature @NatureComms and others coming soon. https://t.co/joo7aMKPtc 2/6
RT @ScienceCrisp: CARMEN (Combinatorial Arrayed Reactions for Multiplexed Evaluation of Nucleic acids) based on Cas13 https://t.co/RGjW8pNE…
CARMEN (Combinatorial Arrayed Reactions for Multiplexed Evaluation of Nucleic acids) based on Cas13 https://t.co/RGjW8pNEF9
CRISPR-based tests may be leading candidates, but this will support development of many promising platforms, which is exactly what we should be doing - as long as we reserve some for production. 6/ https://t.co/CyfUmKgjtS
Why not PCR or @cambearon & @Blaineylab’s CARMEN? 1) we don’t know what nature will throw at us, & 2) any competent adversary will engineer a weapon to evade probes. First ID the threat, then target. https://t.co/CyfUmKgjtS 10/20
Not correct. LAMP assays can suffer from false positives. But they dont have to if set up correctly.
LAMP can also be set up with no false positives today. So people are learning how to avoid that.
@Nichole_Lewis_ I do love it; it’s so fancy. LAMP-based tests are much simpler but suffer from high rate of false positive. see this: https://t.co/m4UrJYenGY And the cool nature paper: https://t.co/F3QVEMTHQS
RT @cheri_ackerman: Our team is excited to introduce CARMEN: a technology that moves us closer to a world where every person who goes to th…
Imagine a test that can detect all possible pathogens for our annual physical: Massively multiplexed nucleic acid detection with Cas13 https://t.co/EPAdQ1QMZA
RT @cambearon: I should add: I'll be talking about CARMEN, our massively multiplexed, Cas13-based technology for nucleic acid detection (ht…
@sciliz @BioFireDX We've been collaborating with Paul Blainey's lab @ MIT on that front, not sure if you saw our paper on this earlier this year? https://t.co/YqCV0xzQrw
RT @cambearon: I should add: I'll be talking about CARMEN, our massively multiplexed, Cas13-based technology for nucleic acid detection (ht…
I should add: I'll be talking about CARMEN, our massively multiplexed, Cas13-based technology for nucleic acid detection (https://t.co/YqCV0xRrQ6)
RT @ScienceCrisp: Massively multiplexed nucleic acid detection using Cas13. Ackerman CM et al. Nature 2020-04-29. https://t.co/RGjW8pNEF9 #…
Massively multiplexed nucleic acid detection using Cas13. Ackerman CM et al. Nature 2020-04-29. https://t.co/RGjW8pNEF9 #CRISPR CARMEN (Combinatorial Arrayed Reactions for Multiplexed Evaluation of Nucleic acids)-Cas13 169 human-associated viruses &
سلام خانم دکتر ثابتی درمورد دارو های انتی بادی یه مسله مهمی رو باید باهتون در میان بگذارم اگه یادتون باشه چند ماه پیش به اقای دکتر کروش حسن زاده ایمیل داده بودین دکتر دسترسی به ایمیلش نداشت الان دکتر میخوان با شما صحبت کنن خواهش میکنم از شما با این شماره 0
RT @CRISPR_papers: Massively multiplexed nucleic acid detection with Cas13. https://t.co/uMGd3KYZdq
Massively multiplexed nucleic acid detection with Cas13. https://t.co/uMGd3KYZdq
RT @GaetanBurgio: After SHERLOCK and DETECTR for nucleic acid detection with #CRISPR, now the massively multiplexed nucleic acid detection…
Cas13を用いた大規模マルチプレックス解析による核酸検出 | Nature | Nature Research https://t.co/E19dyhCpS4
RT @RonDePinho: This diagnostic platform published in @nature from the @broadinstitute detects nearly all pathogens that infect humans. It’…
CRISPR tool scales up to interrogate a huge line-up of viral suspects https://t.co/G0TpYpuSvN Massively multiplexed nucleic acid detection with Cas13 https://t.co/srBbxZftoY https://t.co/DzRg2aERHE
RT @RonDePinho: This diagnostic platform published in @nature from the @broadinstitute detects nearly all pathogens that infect humans. It’…
RT @RonDePinho: This diagnostic platform published in @nature from the @broadinstitute detects nearly all pathogens that infect humans. It’…
This diagnostic platform published in @nature from the @broadinstitute detects nearly all pathogens that infect humans. It’s a GAME CHANGER and it’s highly scalable. #COVID19 https://t.co/lMNG8nvbQh
RT @PardisSabeti: ThankU so much to all the contributors to our most recent massively multiplexed diagnostic efforts, published in @nature…
CARMEN: Combinatorial Arrayed Reactions for Multiplexed Evaluation of Nucleic acids "Massively multiplexed nucleic acid detection using Cas13" Ackerman CM, Myhrvold C [..] Blainey PC, Sabeti PC. Nature 2020-04-29. https://t.co/RGjW8q5g3J
RT @cambearon: Delighted to share with you our latest publication describing CARMEN: a massively multiplexed, Cas13-based technology for nu…
RNAサンプルとCas13を使った分子プローブをそれぞれ色でコードして、マイクロ流路内でエマルジョンの融合反応から、ウィルスを検出する方法。一回の操作で4500サンプルのテストが可能。ブロード研のこの辺り、半端ないペースで論文出てるhttps://t.co/0cUTlopCR2
A terrific opportunity to do cutting edge research in viral diagnostics using CRISPR-based technologies. Some people may say that detecting viruses is important.. 😊 See Cameron's beautiful work: https://t.co/cF6iSDvkoZ and https://t.co/qhXTAwQwvu. The @sab
when it comes to precisely multiplexed nucleic acid detection, CRISPR still takes it all. https://t.co/aUICIJC63o https://t.co/gLCPf9QFTq
RT @ArkitektVenture: This @nature article by @cheri_ackerman, @cambearon, @PardisSabeti, and the @sabeti_lab introduces CARMEN: a #Cas13-ba…
This @nature article by @cheri_ackerman, @cambearon, @PardisSabeti, and the @sabeti_lab introduces CARMEN: a #Cas13-based tool for the massively multiplexed screening of 100+ #viral sequences. Major implications for tracking emerging #infectiousdisease!
RT @LluisMontoliu: @Perestupinya @Avivir Pere si no te has leído todavía el artículo donde describen la nueva técnica #CARMEN te lo recomie…
RT @LluisMontoliu: @Perestupinya @Avivir Pere si no te has leído todavía el artículo donde describen la nueva técnica #CARMEN te lo recomie…
RT @LluisMontoliu: @Perestupinya @Avivir Pere si no te has leído todavía el artículo donde describen la nueva técnica #CARMEN te lo recomie…
RT @LluisMontoliu: @Perestupinya @Avivir Pere si no te has leído todavía el artículo donde describen la nueva técnica #CARMEN te lo recomie…
@Perestupinya @Avivir Pere si no te has leído todavía el artículo donde describen la nueva técnica #CARMEN te lo recomiendo, cumple todas las condiciones. Es largo, complejo e imprescindible, para leer con calma. Es un nuevo Game-changer como dicen los ang
This paper is really cool. Your thoughts, @petervrobinson & @CarolynBertozzi @EnableBio?
In this work from the Sabeti lab, highly-multiplexed CRISPR-based nucleic acid detection shifts diagnostic and surveillance efforts from targeted testing of high-priority samples to comprehensive testing of large sample sets. https://t.co/N4odxUPApO
RT @cambearon: Delighted to share with you our latest publication describing CARMEN: a massively multiplexed, Cas13-based technology for nu…
RT @cambearon: Delighted to share with you our latest publication describing CARMEN: a massively multiplexed, Cas13-based technology for nu…
RT @Sherlock_Bio: Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 ta…
RT @Sherlock_Bio: Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 ta…
RT @Sherlock_Bio: Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 ta…
RT @Pcasbri: "Using CARMEN-Cas13, we developed a multiplexed assay that simultaneously diferentiates all 169 human-associated viruses with…
RT @Pcasbri: "Using CARMEN-Cas13, we developed a multiplexed assay that simultaneously diferentiates all 169 human-associated viruses with…
RT @Sherlock_Bio: Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 ta…
RT @Sherlock_Bio: Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 ta…
RT @Sherlock_Bio: Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 ta…
@T_Greb Well this one... ;) https://t.co/MFKm2D0e75
RT @Sherlock_Bio: Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 ta…
Welcome @Sherlock_bio & @rahulkdhanda to Twitter ✋
RT @Sherlock_Bio: Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 ta…
RT @PardisSabeti: ThankU so much to all the contributors to our most recent massively multiplexed diagnostic efforts, published in @nature…
RT @Sherlock_Bio: Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 ta…
Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 targets, including #COVID19. By screening large sample sets for many pathogens at once, broader detection enables deeper insight. https:/
CRISPR-based chip performs thousands of tests simultaneously to detect viruses - the diagnostic platform, named CARMEN, combines microfluidics with the CRISPR-based detection technology SHERLOCK for massively multiplexed detection https://t.co/JsPCsfeflN h
Indeed, Cas13 applications for diagnostics of human virus including SARS-COV-2 #CRISPR #diagnostics #COVID19 https://t.co/Uw2WGthdWa
Le llegó compañía a ELISA: se viene CARMEN "Using CARMEN-Cas13, we developed a multiplexed assay that simultaneously differentiates all 169 human-associated viruses with ≥10 published genome sequences (...) and the causative agent of the 2020 COVID-19 pan
RT @cheri_ackerman: Our team is excited to introduce CARMEN: a technology that moves us closer to a world where every person who goes to th…
Powerful approach for #infectiousdiseases #detection!
RT @cheri_ackerman: Our team is excited to introduce CARMEN: a technology that moves us closer to a world where every person who goes to th…
RT @cheri_ackerman: Our team is excited to introduce CARMEN: a technology that moves us closer to a world where every person who goes to th…
Using cas13 and microfluidics for multiplexed detection of viral nucleic acids. There are only 169 human-associated viruses with >= 10 genomes! @cheri_ackerman @cambearon @gowthus @CatherineFreije Paul Blainey @PardisSabeti https://t.co/STT3EgDWqD
RT @MarkPlackett1: @innocent_abroad @Anthony_Klan They have your swab DNA sample and they can do lots of things with it. BGI wanted to do D…
RT @MarkPlackett1: @innocent_abroad @Anthony_Klan They have your swab DNA sample and they can do lots of things with it. BGI wanted to do D…
https://t.co/OpT17I8jHe Massively multiplexed nucleic acid detection using Cas13 (with attomolar sensitivity!)
@innocent_abroad @Anthony_Klan They have your swab DNA sample and they can do lots of things with it. BGI wanted to do DNA profiles for $100 ea anyway... https://t.co/ShsE9zdquA
RT @Pcasbri: "Using CARMEN-Cas13, we developed a multiplexed assay that simultaneously diferentiates all 169 human-associated viruses with…
RT @cambearon: Delighted to share with you our latest publication describing CARMEN: a massively multiplexed, Cas13-based technology for nu…
RT @Pcasbri: "Using CARMEN-Cas13, we developed a multiplexed assay that simultaneously diferentiates all 169 human-associated viruses with…
RT @Pcasbri: "Using CARMEN-Cas13, we developed a multiplexed assay that simultaneously diferentiates all 169 human-associated viruses with…
RT @PardisSabeti: ThankU so much to all the contributors to our most recent massively multiplexed diagnostic efforts, published in @nature…
RT @Takeshi_Matsu12: メモ
RT @cambearon: Delighted to share with you our latest publication describing CARMEN: a massively multiplexed, Cas13-based technology for nu…
Trending on PubMed: Massively multiplexed nucleic acid detection using Cas13. https://t.co/fbFtzTrmVz
OMG - Massively multiplexed nucleic acid detection using Cas13 | Nature https://t.co/KTSVBk5DTq
RT @GaetanBurgio: After SHERLOCK and DETECTR for nucleic acid detection with #CRISPR, now the massively multiplexed nucleic acid detection…
メモ
*CRISPR-Cas13 ile viral nükleik asitlerin (suş seviyesinde) ve viral genomlardaki ilaç direnci ilişkili mutasyonların (SNP seviyesinde) multiplex olarak array formatında tespiti.(SARS-CoV-2 dahil) https://t.co/FHnnmomTub
RT @cheri_ackerman: Our team is excited to introduce CARMEN: a technology that moves us closer to a world where every person who goes to th…
A CRISPR based diagnostic test that helps detect several pathogens simultaneously!
RT @davidkmyang: Exciting new platform for multiplexed nucleic acid detection from @sabeti_lab. Proud to have been part of this work https:…
RT @nature: A Nature paper describes a multiple, scalable method for CRISPR-based pathogen detection using self-organizing nanodroplets. ht…
RT @ravboc: The components of CRISPR can be leveraged to detect specific viruses, including SARS-CoV-2, thanks to their high degree of spec…
RT @PardisSabeti: ThankU so much to all the contributors to our most recent massively multiplexed diagnostic efforts, published in @nature…
RT @emulenews: CARMEN-Cas13: Combinatorial Arrayed Reactions for Multiplexed Evaluation of Nucleic acids using Cas13 https://t.co/srBbxZfto…
RT @ScienceCrisp: Massively multiplexed nucleic acid detection using Cas13. Ackerman CM, Myhrvold C [..] Blainey PC, Sabeti PC. Nature 2020…