Effectiveness of immune checkpoint inhibitors in transplant recipients with progressive multifocal #leukoencephalopathy, #EIDjournal, https://t.co/cyJrEwVcCA
What about the role of the microbiota, as has been demonstrated in melanoma treatment?
Zero effectiveness of immune checkpoint inhibitors in kidney recipients with PML (and lymphopenia), small study shows. Brave btw to try checkpoint inhibitors in SOTx patients. Too short follow-up to say anything about graft survival #polyomavirus https://t
RT @GermHunterMD: Sobering report of 3 patients with PML treated with anti-PD1 antibodies. None responded (vs 5/8 in NEJM report by Cortese…
Effectiveness of immune checkpoint inhibitors in transplant recipients with progressive multifocal #leukoencephalopathy, #EIDjournal, https://t.co/cyJrEwVcCA
Checkpoint (PD-1) inhibitors - conflicting data on #pembrolizumab and #nivolumab for #JC virus PML Poor outcome with nivolumab use in transplant patients with #PML https://t.co/EOCc1v83a1
RT @tomayates: Sounds like a trial needed - could a network of centres recruit the numbers needed? https://t.co/bimBLhJEo6
Sounds like a trial needed - could a network of centres recruit the numbers needed?
RT @GermHunterMD: Sobering report of 3 patients with PML treated with anti-PD1 antibodies. None responded (vs 5/8 in NEJM report by Cortese…
RT @GermHunterMD: Sobering report of 3 patients with PML treated with anti-PD1 antibodies. None responded (vs 5/8 in NEJM report by Cortese…
RT @GermHunterMD: Sobering report of 3 patients with PML treated with anti-PD1 antibodies. None responded (vs 5/8 in NEJM report by Cortese…
RT @GermHunterMD: Sobering report of 3 patients with PML treated with anti-PD1 antibodies. None responded (vs 5/8 in NEJM report by Cortese…
RT @GermHunterMD: Sobering report of 3 patients with PML treated with anti-PD1 antibodies. None responded (vs 5/8 in NEJM report by Cortese…
Good find. Why we shouldn’t jump to conclusions on use of PD1 inhibitors in PML based simply on small case series with many confounders. PD1i not without serious toxicity either!
RT @GermHunterMD: Sobering report of 3 patients with PML treated with anti-PD1 antibodies. None responded (vs 5/8 in NEJM report by Cortese…
RT @GermHunterMD: Sobering report of 3 patients with PML treated with anti-PD1 antibodies. None responded (vs 5/8 in NEJM report by Cortese…
Sobering report of 3 patients with PML treated with anti-PD1 antibodies. None responded (vs 5/8 in NEJM report by Cortese et al) #TxID Effectiveness of Immune Checkpoint Inhibitors in Transplant Recipients with Progressive Multifocal Leukoencephalopathy