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@SatyaDash009 Great work! This might be useful to the discussion as we also explored the role of Hb on HbA1c and CAD https://t.co/1ZPpVWjSvl
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@Eric_Fauman This phenomenon confounds MR studies of A1C as an exposure .. a few ways to get around it, including this: https://t.co/wFndmz1Iq6
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @RevistaMFSamfyc: Análisis mediante aleatorización mendeliana de la hemoglobina A1C como factor de riesgo de arteriopatía coronaria http…
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Análisis mediante aleatorización mendeliana de la hemoglobina A1C como factor de riesgo de arteriopatía coronaria https://t.co/OwhBwX5VDj PMID 30659074
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@PeterAttiaMD Here's a disheartening surprise: Mendelian randomization finds HbA1c linked to coronary artery disease, even for variants linked to RBC characteristics and *not* glycemic exposure https://t.co/jwG06eS8Tv
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RT @whsource: "Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease". Suggests that higher A1c (…
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RT @whsource: "Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease". Suggests that higher A1c (…
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RT @whsource: "Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease". Suggests that higher A1c (…
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RT @whsource: "Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease". Suggests that higher A1c (…
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RT @whsource: "Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease". Suggests that higher A1c (…
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RT @whsource: "Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease". Suggests that higher A1c (…
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Seems to me the paper still does not offer any #mechanistic explanation to the basic question: Why does non-enzymatic #glycation of #hemobglobin (elevated #HbA1c) lead to #CAD? Is HbA1c only a proxy for other #glycated proteins with direct effect on the ri
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RT @whsource: "Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease". Suggests that higher A1c (…
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Higher A1C was associated with increased CAD risk when using only glycemic variants (OR 2.23 [1.73, 2.89], P = 1.0 × 10−9) and when using only erythrocytic variants (OR 1.30 [1.08, 1.57], P = 0.006).
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RT @whsource: "Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease". Suggests that higher A1c (…
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"Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease". Suggests that higher A1c (marker of avg blood sugar) is a major heart disease risk factor, but surprisingly blood sugar is only part of the explanation. http
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Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease https://t.co/bVq6ASMUaY via @instapaper
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RT @sciencescanner: Fascinating! Strongly suggests Hba1c is not just a marker for CAD risk in CAD but itself a contributory cause https://t…
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RT @sciencescanner: Fascinating! Strongly suggests Hba1c is not just a marker for CAD risk in CAD but itself a contributory cause https://t…
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Fascinating! Strongly suggests Hba1c is not just a marker for CAD risk in CAD but itself a contributory cause
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According to a new study by @mfhivert & colleagues in @ADA_Journals, genetic evidence supports a causal link between higher A1C and higher risk of coronary artery disease. For more: https://t.co/yTZU1LndRA https://t.co/N3oLRgd9tH
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According to a new study by @mfhivert & colleagues in @ADA_Journals, genetic evidence supports a causal link between higher A1C and higher risk of coronary artery disease. For more: https://t.co/yTZU1LndRA https://t.co/aP0jCrOaJc
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @Mendelian_lit: Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease. https://t.co/WavsTu2nRP
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RT @Mendelian_lit: Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease. https://t.co/WavsTu2nRP
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Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease. https://t.co/WavsTu2nRP
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Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease. https://t.co/K5KdT24GU2
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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RT @moreno_perez_o: 2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJ…
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2 recent Diabetes Care studies The ALLHAT https://t.co/M8gmTcHjQo Hb A1c as a Risk Factor for CAD https://t.co/VGl4hOIJjB, which reaffirm the importance of HbA1c and glycemic variability in morbi-mortality “BESIDES metabolic control, NOT INSTEAD of” Evid B
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Mendelian Randomization Analysis of HbA1c as a Risk Factor for Coronary Artery Disease. Genetically increased A1C was associated with higher CAD risk OR 1.6, and extends beyond its reflection of ambient glycemia ☝🏻 @sociedadSEEN @SEDiabetes @secardiologia
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RT @DanielJDrucker: Complex Calculations. Genetic evidence supports a causal link between higher A1C and higher CAD risk driven by glycemic…
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Complex Calculations. Genetic evidence supports a causal link between higher A1C and higher CAD risk driven by glycemic and erythrocytic, glycemia-independent factors. https://t.co/a9PABRCTOv