@pkerpedjiev I like the notion of decomposing a GWAS into separate biological signals, like https://t.co/1B5Xx7AIy8, https://t.co/DPSeSqJif6 https://t.co/hXUMriDz77 or this analysis I did of kidney stones last month: https://t.co/BYxpYX6uuI https://t.co/D
pull this & map the many associationes of Type 2 diabetes... Then? You will understand why I call it, "diabet(es)"
@JimJohnsonSci @AliceYYCheng The new portal is finished!
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis Page 9 mentions HOMA https://t.co/PDimfIrwo9
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis @vision_quality @gerdosi Open https://t.co/PDimfIrwo9
RT @KPortalNetwork: There's also a new visualization (https://t.co/owwXmMFXzN) that lets you explore work from @miriam_udler and colleagues…
There's also a new visualization (https://t.co/owwXmMFXzN) that lets you explore work from @miriam_udler and colleagues (https://t.co/nP3ZXuPAF9), clustering T2D-associated variants by their associations with other relevant traits to illuminate #T2D mechan
@mkruk @larsakepersson @paimadhu Check out Ron Ma's article choices: Clarke et al (2010) https://t.co/JJszF8hqsc Florez et al (2018) https://t.co/aWe7XT0Wpk
#PLOSMedicine: Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis https://t.co/A0nvfS31VY
Very cool paper about #GWAS soft-clustering. Finally a way to analyze statistically the fact that a gene's product has multiple roles in the cell and or pathway. https://t.co/YIrC7ON1BR
Great paper. GWAS Soft clustering finally takes into consideration the fact that gene products (protein or other) have functions in more than one pathway https://t.co/m9kiGZ1CPF
#PersonalisedMedicine & management of Type 2 #Diabetes #NIDDM #genomics https://t.co/gMqOs6SikE
Two interesting papers this year used cluster analyses to identify subgroups of diabetes @emma_ahlqvist https://t.co/YTlBn64WJl and @miriam_udler https://t.co/TpKeWDyODc Potentially an important shift from our traditional views of 'T1D' and 'T2D'.
#PLOSMedicine: Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms ... https://t.co/irziQ0Ch2V
In a new @PLOSMedicine study, researchers used a number of genetic datasets to identify five dominant pathways leading to increased risk of #diabetes, based on genetic variants. Rethinking Diabetes: https://t.co/wsWKDv6Dmv. Study: https://t.co/uIqupWGNKa #
Today's new phrase: " Bayesian non-negative matrix factorization" or how to cluster genetic variants to predict insulin secretory dysfunction or insulin resistance and tailor treatments for patients with T2D. Cool stuff! https://t.co/45Bvl9MESS
#PLOSMedicine: Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms ... https://t.co/fykH1j4sAU
Selon une étude publiée dans @PLOSMedicine, le diabète de type 2 serait constitué de cinq sous-types génomique distincts. Cette découverte permettrait à terme un diagnostic, une prise en charge des patients personnalisée par sous-type. #medecine https://t.
RT @broadinstitute: In @PLOSMedicine: Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms ... ht…
RT @broadinstitute: In @PLOSMedicine: Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms ... ht…
In @PLOSMedicine: Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms ... https://t.co/h9meYw0Cao
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @Drlipid: Of interest: T2D genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: five genetic subt…
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
Type 2 diabetes just got more complicated on one hand but possibly easier to treat on the other. How is that possible? Apparently there are 5 different types of it with different features. https://t.co/bPYNRqDTud #PrecisionMedicine #type2diabetes #Genetics
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
And for our readers who have medical or scientific backgrounds... https://t.co/HkiwI7bcHb
RT @Drlipid: Of interest: T2D genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: five genetic subt…
Diabetes is related to insulin resistance and deficiency? Who knew? Now all we need do is genetically modify live humans to treat it. #duh
Of interest: T2D genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: five genetic subtypes of T2D, two of which are related to insulin deficiency and three of which are related to insulin resistance https://t.co/ZHFP
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
Genetic approach to deconstruct type 2 diabetes patient heterogenity: https://t.co/emODod1U9c
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @JimJohnsonSci: Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
Lots of interesting work coming out on the clustering of type 2 diabetes subtypes. https://t.co/yP1HyLnERt
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis https://t.co/TpuwgsOH3K
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @CristobMorales: https://t.co/AhhU5LfPRS Más cerca de la medicina de precisión en diabetes: “Classification by these genetic pathways ma…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/GnzpXOZ9nb . Udler describe 5 cluster genetic loci y su fenotipo clínico https://t.co/1lPj5myIOv (Free) Sólo coincidencia? El 30% de los sujetos tienen un cluster gran dominante, sugiriendo… https
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
RT @isidoro_cano: Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotip…
Ahlqvist describe 5 fenotipos DM2 y sus genes https://t.co/pXyHFvx2K2. Udler describe 5 cluster genetic loci y su fenotipo clínico https://t.co/UAmjKP389f (Free) Sólo coincidencia? El 30% de los sujetos tienen un cluster gran dominante, sugiriendo estrateg
RT @CristobMorales: https://t.co/AhhU5LfPRS Más cerca de la medicina de precisión en diabetes: “Classification by these genetic pathways ma…
Grateful we have the information & please eat low starch/carb, do manage your stress, get some sun everyday, & keep up w/exercise-do a little more each day.
For 5 years, I believed this & after research into epigenetics I understand that T2DM is epigenetic changes in cells that make up specific organs: NAFLD, NAFPD, pancreas shut down, cell resistance, dysfunctional micro biome. https://t.co/hkdqDkdjKU
Genomic study brings us closer to precision medicine for type 2 diabetes: https://t.co/xDfrZsVjTL Published this week in @PLOSMedicine https://t.co/4QGhmqBdOG
RT @EitanHoch: A first step toward using genetics to identify subtypes of type 2 diabetes: From Miriam Udler @broadinstitute https://t.co/v…
RT @EitanHoch: A first step toward using genetics to identify subtypes of type 2 diabetes: From Miriam Udler @broadinstitute https://t.co/v…
RT @EitanHoch: A first step toward using genetics to identify subtypes of type 2 diabetes: From Miriam Udler @broadinstitute https://t.co/v…
RT @EitanHoch: A first step toward using genetics to identify subtypes of type 2 diabetes: From Miriam Udler @broadinstitute https://t.co/v…
#PLOSMedicine: Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms ... https://t.co/Cha355j074
RT @CristobMorales: https://t.co/AhhU5LfPRS Más cerca de la medicina de precisión en diabetes: “Classification by these genetic pathways ma…
RT @CristobMorales: https://t.co/AhhU5LfPRS Más cerca de la medicina de precisión en diabetes: “Classification by these genetic pathways ma…
RT @CristobMorales: https://t.co/AhhU5LfPRS Más cerca de la medicina de precisión en diabetes: “Classification by these genetic pathways ma…
RT @CristobMorales: https://t.co/AhhU5LfPRS Más cerca de la medicina de precisión en diabetes: “Classification by these genetic pathways ma…
https://t.co/AhhU5LfPRS Más cerca de la medicina de precisión en diabetes: “Classification by these genetic pathways may offer a step toward genetically anchored but physiologically informed diagnosis, surveillance, and management of patients with T2D” htt
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis @PLOSMedicine https://t.co/YVeqemZzdJ
Patients with type 2 diabetes, based on their genetic variants, can be grouped into five clusters that reflect different disease mechanisms and could help personalize treatments in the future, according to a new study. https://t.co/ZbHN2bWFNF … https://t.c
RT @CtdGrupo: Patients with type 2 diabetes, based on their genetic variants, can be grouped into five clusters that reflect different dise…
RT @CtdGrupo: Patients with type 2 diabetes, based on their genetic variants, can be grouped into five clusters that reflect different dise…
RT @CtdGrupo: Patients with type 2 diabetes, based on their genetic variants, can be grouped into five clusters that reflect different dise…
Genomic study brings us closer to precision medicine for type 2 diabetes: https://t.co/UNOjUXAGEj https://t.co/6EAf0mOFIq
Patients with type 2 diabetes, based on their genetic variants, can be grouped into five clusters that reflect different disease mechanisms and could help personalize treatments in the future, according to a new study. https://t.co/0d0XYIoR7i
@EMbunwe in case you are interested https://t.co/BUSPFYx2FS
RT @EitanHoch: A first step toward using genetics to identify subtypes of type 2 diabetes: From Miriam Udler @broadinstitute https://t.co/v…
RT @EitanHoch: A first step toward using genetics to identify subtypes of type 2 diabetes: From Miriam Udler @broadinstitute https://t.co/v…
RT @EitanHoch: A first step toward using genetics to identify subtypes of type 2 diabetes: From Miriam Udler @broadinstitute https://t.co/v…
Really interesting study suggests novel subtypes of type 2 diabetes - here based on genetic variants associated with #type2diabetes
RT @robo_gwas: Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clusterin…
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis. https://t.co/55rrvtoPZy
#PLOSMedicine: Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms ... https://t.co/qYUEvae2zK exciting work from MIriam Udler and many others. Glad I was also part!
RT @EitanHoch: A first step toward using genetics to identify subtypes of type 2 diabetes: From Miriam Udler @broadinstitute https://t.co/v…
RT @EitanHoch: A first step toward using genetics to identify subtypes of type 2 diabetes: From Miriam Udler @broadinstitute https://t.co/v…