| Title |
Pediatric Complicated Pneumonia Caused by Streptococcus pneumoniae Serotype 3 in 13-Valent Pneumococcal Conjugate Vaccinees, Portugal, 2010–2015
|
|---|---|
| Published in |
Emerging Infectious Diseases, July 2018
|
| DOI | 10.3201/eid2407.180029 |
| Pubmed ID | |
| Authors |
Catarina Silva-Costa, Maria João Brito, Marcos D. Pinho, Ana Friães, Sandra I. Aguiar, M. Ramirez, Jose Melo-Cristino |
| Abstract |
Despite use of 7-valent pneumococcal conjugate vaccine, incidence of pleural effusion and empyema (pediatric complicated pneumococcal pneumonia [PCPP]) is reportedly increasing globally. We cultured and performed PCR on 152 pleural fluid samples recovered from pediatric patients in Portugal during 2010-2015 to identify and serotype Streptococcus pneumoniae. We identified only 17 cases by culture, but molecular methods identified S. pneumoniae in 68% (92/135) of culture-negative samples. The most frequent serotypes were 3, 1, and 19A, together accounting for 62% (68/109) of cases. Nineteen cases attributable to 13-valent pneumococcal conjugate vaccine (PCV13) serotypes (mostly serotype 3) were detected among 22 children age-appropriately vaccinated with PCV13. The dominance of the additional serotypes included in PCV13 among PCPP cases in Portugal continues, even with PCV13 available on the private market (without reimbursement) since 2010 and with average annual coverage of 61% among age-eligible children. Our data suggest reduced effectiveness of PCV13 against serotype 3 PCPP. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 3 | 75% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 71 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 13% |
| Researcher | 8 | 11% |
| Student > Postgraduate | 6 | 8% |
| Student > Bachelor | 6 | 8% |
| Other | 4 | 6% |
| Other | 14 | 20% |
| Unknown | 24 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 30% |
| Biochemistry, Genetics and Molecular Biology | 9 | 13% |
| Immunology and Microbiology | 3 | 4% |
| Nursing and Health Professions | 3 | 4% |
| Agricultural and Biological Sciences | 2 | 3% |
| Other | 3 | 4% |
| Unknown | 30 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 June 2018.
All research outputs
#7,567,343
of 23,342,232 outputs
Outputs from Emerging Infectious Diseases
#5,423
of 9,205 outputs
Outputs of similar age
#128,392
of 328,839 outputs
Outputs of similar age from Emerging Infectious Diseases
#73
of 120 outputs
Altmetric has tracked 23,342,232 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 9,205 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 44.0. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
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