Title |
Widespread Treponema pallidum Infection in Nonhuman Primates, Tanzania - Volume 24, Number 6—June 2018 - Emerging Infectious Diseases journal - CDC
|
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Published in |
Emerging Infectious Diseases, June 2018
|
DOI | 10.3201/eid2406.180037 |
Pubmed ID | |
Authors |
Idrissa S. Chuma, Emmanuel K. Batamuzi, D. Anthony Collins, Robert D. Fyumagwa, Luisa K. Hallmaier-Wacker, Rudovick R. Kazwala, Julius D. Keyyu, Inyasi A. Lejora, Iddi F. Lipende, Simone Lüert, Filipa M.D. Paciência, Alexander Piel, Fiona A. Stewart, Dietmar Zinner, Christian Roos, Sascha Knauf |
Abstract |
We investigated Treponema pallidum infection in 8 nonhuman primate species (289 animals) in Tanzania during 2015-2017. We used a serologic treponemal test to detect antibodies against the bacterium. Infection was further confirmed from tissue samples of skin-ulcerated animals by 3 independent PCRs (polA, tp47, and TP_0619). Our findings indicate that T. pallidum infection is geographically widespread in Tanzania and occurs in several species (olive baboons, yellow baboons, vervet monkeys, and blue monkeys). We found the bacterium at 11 of 14 investigated geographic locations. Anogenital ulceration was the most common clinical manifestation; orofacial lesions also were observed. Molecular data show that nonhuman primates in Tanzania are most likely infected with T. pallidum subsp. pertenue-like strains, which could have implications for human yaws eradication. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | 22% |
Netherlands | 1 | 11% |
United States | 1 | 11% |
Australia | 1 | 11% |
Mexico | 1 | 11% |
Unknown | 3 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 56% |
Scientists | 2 | 22% |
Science communicators (journalists, bloggers, editors) | 1 | 11% |
Practitioners (doctors, other healthcare professionals) | 1 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 50 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 18% |
Student > Ph. D. Student | 8 | 16% |
Researcher | 5 | 10% |
Student > Bachelor | 4 | 8% |
Other | 4 | 8% |
Other | 13 | 26% |
Unknown | 7 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 16% |
Medicine and Dentistry | 7 | 14% |
Biochemistry, Genetics and Molecular Biology | 5 | 10% |
Veterinary Science and Veterinary Medicine | 5 | 10% |
Social Sciences | 3 | 6% |
Other | 13 | 26% |
Unknown | 9 | 18% |