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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline forCYP2D6andCYP2C19Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

Overview of attention for article published in Clinical Pharmacology & Therapeutics, June 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

Mentioned by

news
2 news outlets
twitter
8 tweeters
video
1 video uploader

Citations

dimensions_citation
462 Dimensions

Readers on

mendeley
492 Mendeley
Title
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline forCYP2D6andCYP2C19Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors
Published in
Clinical Pharmacology & Therapeutics, June 2015
DOI 10.1002/cpt.147
Pubmed ID
Authors

JK Hicks, JR Bishop, K Sangkuhl, DJ Müller, Y Ji, SG Leckband, JS Leeder, RL Graham, DL Chiulli, A LLerena, TC Skaar, SA Scott, JC Stingl, TE Klein, KE Caudle, A Gaedigk

Abstract

Selective Serotonin Reuptake Inhibitors (SSRIs) are primary treatment options for major depressive and anxiety disorders. CYP2D6 and CYP2C19 polymorphisms can influence the metabolism of SSRIs thereby affecting drug efficacy and safety. We summarize evidence from the published literature supporting these associations and provide dosing recommendations for fluvoxamine, paroxetine, citalopram, escitalopram and sertraline based on CYP2D6 and/or CYP2C19 genotype (updates at www.pharmgkb.org). This article is protected by copyright. All rights reserved.

Twitter Demographics

The data shown below were collected from the profiles of 8 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 492 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 <1%
Mexico 1 <1%
Unknown 487 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 74 15%
Researcher 73 15%
Student > Bachelor 64 13%
Student > Ph. D. Student 59 12%
Student > Doctoral Student 43 9%
Other 110 22%
Unknown 69 14%
Readers by discipline Count As %
Medicine and Dentistry 124 25%
Pharmacology, Toxicology and Pharmaceutical Science 95 19%
Biochemistry, Genetics and Molecular Biology 78 16%
Agricultural and Biological Sciences 39 8%
Nursing and Health Professions 17 3%
Other 57 12%
Unknown 82 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2021.
All research outputs
#1,294,069
of 18,422,743 outputs
Outputs from Clinical Pharmacology & Therapeutics
#186
of 3,737 outputs
Outputs of similar age
#20,775
of 242,680 outputs
Outputs of similar age from Clinical Pharmacology & Therapeutics
#8
of 27 outputs
Altmetric has tracked 18,422,743 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,737 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,680 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.