Title |
Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT
|
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Published in |
Transplantation and Cellular Therapy, May 2017
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DOI | 10.1016/j.bbmt.2017.04.026 |
Pubmed ID | |
Authors |
Jennifer Heimall, Rebecca H. Buckley, Jennifer Puck, Thomas A. Fleisher, Andrew R. Gennery, Elie Haddad, Benedicte Neven, Mary Slatter, Skinner Roderick, K. Scott Baker, Andrew C. Dietz, Christine Duncan, Linda M. Griffith, Luigi Notarangelo, Michael A. Pulsipher, Morton J. Cowan |
Abstract |
Severe Combined Immunodeficiency (SCID) is effectively treated with HCT with overall survival approaching 90% in contemporary reports. However, survivors are at risk for development of late complications due to the variable durability of high quality immune function, underlying genotype of SCID, comorbidities due to infections in the pre- and post- transplant period and use of conditioning pre-transplant. An international group of transplant experts was convened in 2016 to review the current knowledge of late effects seen in SCID patients following HCT, and develop recommendations for screening and monitoring for late effects. This report provides recommendations for screening and management of pediatric and adult SCID patients treated with HCT. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 6 | 75% |
Unknown | 2 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 4 | 50% |
Members of the public | 3 | 38% |
Scientists | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 72 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 9 | 13% |
Student > Master | 7 | 10% |
Student > Bachelor | 7 | 10% |
Researcher | 6 | 8% |
Student > Ph. D. Student | 6 | 8% |
Other | 11 | 15% |
Unknown | 26 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 26 | 36% |
Nursing and Health Professions | 8 | 11% |
Immunology and Microbiology | 4 | 6% |
Engineering | 2 | 3% |
Physics and Astronomy | 1 | 1% |
Other | 1 | 1% |
Unknown | 30 | 42% |