↓ Skip to main content

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update

Overview of attention for article published in Clinical Pharmacology & Therapeutics, May 2013
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#50 of 3,512)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

news
4 news outlets
blogs
2 blogs
twitter
4 tweeters

Citations

dimensions_citation
598 Dimensions

Readers on

mendeley
436 Mendeley
Title
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update
Published in
Clinical Pharmacology & Therapeutics, May 2013
DOI 10.1038/clpt.2013.105
Pubmed ID
Authors

S A Scott, K Sangkuhl, C M Stein, J-S Hulot, J L Mega, D M Roden, T E Klein, M S Sabatine, J A Johnson, A R Shuldiner

Abstract

Cytochrome P450 (CYP)2C19 catalyzes the bioactivation of the antiplatelet prodrug clopidogrel, and CYP2C19 loss-of-function alleles impair formation of active metabolites, resulting in reduced platelet inhibition. In addition, CYP2C19 loss-of-function alleles confer increased risks for serious adverse cardiovascular (CV) events among clopidogrel-treated patients with acute coronary syndromes (ACSs) undergoing percutaneous coronary intervention (PCI). Guideline updates include emphasis on appropriate indication for CYP2C19 genotype-directed antiplatelet therapy, refined recommendations for specific CYP2C19 alleles, and additional evidence from an expanded literature review (updates at http://www.pharmgkb.org).

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 436 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 <1%
Chile 1 <1%
Netherlands 1 <1%
Colombia 1 <1%
Brazil 1 <1%
India 1 <1%
Portugal 1 <1%
Unknown 427 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 70 16%
Student > Bachelor 61 14%
Student > Master 61 14%
Student > Ph. D. Student 54 12%
Student > Doctoral Student 40 9%
Other 85 19%
Unknown 65 15%
Readers by discipline Count As %
Medicine and Dentistry 124 28%
Pharmacology, Toxicology and Pharmaceutical Science 77 18%
Biochemistry, Genetics and Molecular Biology 65 15%
Agricultural and Biological Sciences 49 11%
Nursing and Health Professions 6 1%
Other 37 8%
Unknown 78 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 48. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2020.
All research outputs
#505,799
of 16,722,463 outputs
Outputs from Clinical Pharmacology & Therapeutics
#50
of 3,512 outputs
Outputs of similar age
#5,241
of 162,698 outputs
Outputs of similar age from Clinical Pharmacology & Therapeutics
#2
of 37 outputs
Altmetric has tracked 16,722,463 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,512 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 162,698 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.