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Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity - Volume 23, Number 2—February 2017 - Emerging Infectious Diseases journal - CDC

Overview of attention for article published in Emerging Infectious Diseases, February 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

news
3 news outlets
blogs
2 blogs
twitter
10 X users

Citations

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55 Dimensions

Readers on

mendeley
53 Mendeley
Title
Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity - Volume 23, Number 2—February 2017 - Emerging Infectious Diseases journal - CDC
Published in
Emerging Infectious Diseases, February 2017
DOI 10.3201/eid2302.161072
Pubmed ID
Authors

Hongbo Guo, Erik de Vries, Ryan McBride, Jojanneke Dekkers, Wenjie Peng, Kim M. Bouwman, Corwin Nycholat, M. Helene Verheije, James C. Paulson, Frank J.M. van Kuppeveld, Cornelis A.M. de Haan

Abstract

Emergence and intercontinental spread of highly pathogenic avian influenza A(H5Nx) virus clade 2.3.4.4 is unprecedented. H5N8 and H5N2 viruses have caused major economic losses in the poultry industry in Europe and North America, and lethal human infections with H5N6 virus have occurred in Asia. Knowledge of the evolution of receptor-binding specificity of these viruses, which might affect host range, is urgently needed. We report that emergence of these viruses is accompanied by a change in receptor-binding specificity. In contrast to ancestral clade 2.3.4 H5 proteins, novel clade 2.3.4.4 H5 proteins bind to fucosylated sialosides because of substitutions K222Q and S227R, which are unique for highly pathogenic influenza virus H5 proteins. North American clade 2.3.4.4 virus isolates have retained only the K222Q substitution but still bind fucosylated sialosides. Altered receptor-binding specificity of virus clade 2.3.4.4 H5 proteins might have contributed to emergence and spread of H5Nx viruses.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 2%
Unknown 52 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 23%
Student > Ph. D. Student 7 13%
Student > Master 7 13%
Student > Bachelor 6 11%
Student > Postgraduate 3 6%
Other 7 13%
Unknown 11 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 26%
Biochemistry, Genetics and Molecular Biology 11 21%
Veterinary Science and Veterinary Medicine 7 13%
Immunology and Microbiology 5 9%
Unspecified 1 2%
Other 4 8%
Unknown 11 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 38. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2024.
All research outputs
#1,076,750
of 25,537,395 outputs
Outputs from Emerging Infectious Diseases
#1,219
of 9,726 outputs
Outputs of similar age
#24,716
of 449,817 outputs
Outputs of similar age from Emerging Infectious Diseases
#23
of 161 outputs
Altmetric has tracked 25,537,395 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,726 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.9. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 449,817 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 161 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.